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§3.7.1 · BotanicalsDeliriants

Datura

Acute: Extreme riskDependency: Lower risk

Images

Quick reference

Routes
Oral
Form
Seeds
Shulgin rating
++

Experience

Primary effects

  • Even at a single seed, causes a "heady strangeness" and a mildly dissociative state, with a sense of disconnection from the visible world and greater visual acuity.
  • Can induce vivid, sometimes weird dreams and, at higher doses, full delirium and hallucinations (a sign of near-fatal overdose).

Peak character

  • Subtle psychoactivity, leading to self-reflection and a neutral mood, possibly a mild feeling of disconnection and fragmented sensory processing.

Negatives / side effects

  • Extremely toxic; delirium and hallucinations are signs of near-fatal overdose, carrying high risk of death.
  • Highly variable potency even within a single plant's seeds makes accurate dosing impossible, with a single seed's strength potentially varying seven-fold.
  • Adverse effects include seizures, hyperthermia, cardiovascular issues, organ failure, rhabdomyolysis, and permanent brain damage.
  • Users often experience impaired judgment, memory loss, and may become out of control, unaware of their actions.

Aftereffects / comedown

  • Sleep can be disturbed by vivid dreams, dry mouth, and frequent urination.
  • Next-day effects may include a headache, a persistent "background buzz," and a lingering sense of strangeness.

Reagent testing

Recommended reagents
Expected reactions
MarquisOrange/brown (tropane alkaloids — atropine, scopolamine)
MandelinYellow → orange/brown

Adulterant detection: Datura stramonium — atropine/scopolamine/hyoscyamine. All species of Datura are extremely dangerous with a very narrow margin between 'effective' and lethal doses. Reagents confirm alkaloid presence but cannot ensure safety.

CRITICAL DANGER: Datura is considered one of the most dangerous psychoactive plants. The difference between an 'active' dose and a lethal dose is extremely small and variable between plants and individual alkaloid concentrations. Reagent testing cannot ensure safety with this plant.

Source

Reference fields and narrative for Datura extracted from The Drug Users Bible by Dominic Milton Trott (MxZero Publishing, 2022).

drugusersbible.com

Harm reduction notice

This platform provides educational and harm-reduction information adapted from public reference material. It does not endorse, encourage, or facilitate drug use. It is not medical advice. If you or someone near you may be in a medical emergency, contact local emergency services immediately.