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§2.2.4 · ChemicalsPsychedelics

2C-B

2,5-dimethoxy-4-bromophenethylamine

Also known as Nexus · Bees · Venus · 2cb

Acute: Moderate riskDependency: Lower risk

Images

Quick reference

Form
Oral
Shulgin rating
++

Duration

Onset
1 Hours
Total duration
6 Hours

Experience

Primary effects

  • Induces a mild psychedelic ambiance with enhanced color vibrancy and subtle visual morphing.
  • Creates a physical awareness described as having a tactile or entactogenic edge.
  • Shulgin noted its potential as an aphrodisiac, enhancing sexual human contact and sensation.

Peak character

  • Headspace is stable and controllable; user remains fully functional, able to suppress the experience.
  • Promotes a content and happy mood, with a sense of calmness and serenity.
  • Mind tends to wander and drift, but is still under normal functional control.

Negatives / side effects

  • Extreme dose sensitivity means slight changes in dosage can lead to significantly different effects.
  • Can cause initial chilly feelings, shivers, and cold fingers (vasoconstriction); some users report body load issues at higher doses.

Aftereffects / comedown

  • Drifts back to baseline without a significant comedown, leaving a comfortable and positive mood.
  • No hangover and good sleep reported; leaves a post-trip afterglow.

Reference dosage

Reference ranges from third-party harm-reduction databases. Individual response varies enormously — start lower than you think.

Any route
threshold2mg+
light5mg+
common15mg+
strong25mg+

Reagent testing

Recommended reagents
Expected reactions
MarquisYellow → green (slow)
MeckeBlue/green
FroehdeOrange → red/brown
LiebermannOrange → brown

Adulterant detection: Marquis going immediately dark/black suggests amphetamine contamination. Ehrlich turning purple would indicate indole adulterant.

2C-B has a distinctive slow Marquis reaction. Rushing to read results early gives false negatives. Use at least two reagents.

Source

Reference fields and narrative for 2C-B extracted from The Drug Users Bible by Dominic Milton Trott (MxZero Publishing, 2022).

drugusersbible.com

Harm reduction notice

This platform provides educational and harm-reduction information adapted from public reference material. It does not endorse, encourage, or facilitate drug use. It is not medical advice. If you or someone near you may be in a medical emergency, contact local emergency services immediately.