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§2.2.7 · ChemicalsPsychedelics

2C-E

2,5-dimethoxy-4-ethylphenethylamine

Also known as 2ce · Europa

Acute: Moderate riskDependency: Lower risk

Images

Quick reference

Routes
Oral
Form
Pill

Duration

Onset
30 Minutes
Total duration
8 Hours

Experience

Primary effects

  • A mild, introspective headspace develops, with enhanced visual coloration and a developing psychedelic sheen.
  • Causes a tingly body sensation, particularly in hands, and a subjective feeling of mood elevation.

Peak character

  • Mind play and deep introspection are predominant, with a drifting, hypnotic headiness.
  • Characterized by profound consideration and pensive contemplation, with no significant euphoria or mood lift.

Negatives / side effects

  • Produces a high body load for many users.
  • Has a very steep dose-response curve; even small increases in dose can lead to a significant jump in intensity.
  • Low doses can be highly intense; 15mg has been reported to cause a 'full freakout'.

Aftereffects / comedown

  • Intensity subsides, but deep thought and introspection continue to roll.
  • Fades slowly, leaving a low level of contentedness and normal psychedelic lassitude and fatigue.
  • May result in a mild headache on awakening, considered part of the body load.

Reference dosage

Reference ranges from third-party harm-reduction databases. Individual response varies enormously — start lower than you think.

Any route
threshold2mg+
light5mg+
common10mg+
strong15mg+
heavy25mg+

Reagent testing

Recommended reagents
Expected reactions
MarquisYellow → green
MeckeBlue → green
FroehdeOrange → brown
LiebermannOrange → brown

Adulterant detection: Rapid black with Marquis indicates amphetamines.

More potent than 2C-B by weight — precise dosing is critical; testing strongly advised.

Source

Reference fields and narrative for 2C-E extracted from The Drug Users Bible by Dominic Milton Trott (MxZero Publishing, 2022).

drugusersbible.com

Harm reduction notice

This platform provides educational and harm-reduction information adapted from public reference material. It does not endorse, encourage, or facilitate drug use. It is not medical advice. If you or someone near you may be in a medical emergency, contact local emergency services immediately.