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§3.4.24 · BotanicalsBotanical Sedatives

Wild Lettuce

Acute: Lower riskDependency: Lower risk

Images

Quick reference

Routes
Smoked / Oral
Form
Leaves
Shulgin rating
+/+

Experience

Primary effects

  • Wild lettuce provides a distinct sedative and anxiolytic experience, particularly when smoked or consumed as a tea.
  • It induces a 'heady presence' and a background sedating psychoactivity that is noticeable but minor.

Peak character

  • The experience is more anxiolytic (anxiety-reducing) than sleep-inducing, though it does contribute to sedation.
  • It subtly alters perception.

Aftereffects / comedown

  • Can lead to a deep and prolonged sleep, potentially exceeding 10 hours, particularly with very large doses.

Reagent testing

Recommended reagents
Expected reactions
MarquisFaint orange (lactucopicrin — sesquiterpene lactone)

Adulterant detection: Lactuca virosa — lactucin/lactucopicrin. Limited colorimetric reactivity. Low adulteration risk for dried herb.

Mild colorimetric reaction; Marquis provides limited confirmation.

Source

Reference fields and narrative for Wild Lettuce extracted from The Drug Users Bible by Dominic Milton Trott (MxZero Publishing, 2022).

drugusersbible.com

Harm reduction notice

This platform provides educational and harm-reduction information adapted from public reference material. It does not endorse, encourage, or facilitate drug use. It is not medical advice. If you or someone near you may be in a medical emergency, contact local emergency services immediately.