§2.7.3 · Chemicals › Empathogens & Entactogens

MDAI

5,6-methylenedioxy-2-aminoindane

Acute: Moderate riskDependency: Moderate risk Test for fentanyl

Images

Quick reference

Routes

Oral

Form

Powder

Shulgin rating

Duration

Onset

45 Minutes

Total duration

5 Hours

Experience

Primary effects

MDAI provides a pleasant, uplifting experience with an empathogenic edge, making one feel good.

Peak character

The peak can induce feelings of enhanced attraction, perceiving others as more beautiful.

Negatives / side effects

MDAI is considered relatively benign and not particularly problematic in terms of risk.

Aftereffects / comedown

The 'magic' of the experience may dissipate after repeated use, potentially due to perceptual adjustment beyond tolerance.

Reference dosage

Reference ranges from third-party harm-reduction databases. Individual response varies enormously — start lower than you think.

Any route

threshold	20mg+
light	60+
common	100mg+
strong	175mg+

Reagent testing

Recommended reagents

Marquis Mecke Froehde

Expected reactions

Marquis	Purple → dark
Mecke	Blue → dark
Froehde	Blue → dark

Adulterant detection: 5,6-methylenedioxy-2-aminoindane. Reagent profile resembles MDMA/MDA. Limited specific data.

Often found in 'ecstasy' supply as adulterant or substitute; testing helps identify.

Source

Reference fields and narrative for MDAI extracted from The Drug Users Bible by Dominic Milton Trott (MxZero Publishing, 2022).

drugusersbible.com

Harm reduction notice

This platform provides educational and harm-reduction information adapted from public reference material. It does not endorse, encourage, or facilitate drug use. It is not medical advice. If you or someone near you may be in a medical emergency, contact local emergency services immediately.