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§2.7.7 · ChemicalsEmpathogens & Entactogens

Methylone

3,4-methylenedioxy-N-methylcathinone

Also known as MDMC · βk-MDMA · M1 · Ease · Explosion

Acute: Moderate riskDependency: Moderate risk Test for fentanyl

Images

Quick reference

Routes
Oral
Form
Powder

Duration

Onset
30 Minutes
Total duration
3 Hours

Experience

Primary effects

  • Induces a clear uplift and stimulating buzz in the head, described as pleasant.
  • Causes a general warmth, mood lift, and a dreamy stimulation.
  • Can have a mild empathogenic feel, potentially enhancing social situations.

Peak character

  • Characterized by a pleasing vibe, general contentment, and a semi-euphoric buzz.
  • The experience settles into a plateau of general well-being, described as nice and gentle.

Negatives / side effects

  • Higher doses can cause worrying heart rate and blood pressure increases, as well as chest pains.
  • Even at moderate doses, elevated blood pressure and pulse were observed (183/94 and 69 respectively).
  • Hands may feel cold and clammy, and slight chest trembles can occur.

Aftereffects / comedown

  • The next morning, users may experience a slight headache.
  • Sleep can be interrupted, leading to a not-too-pleasant headiness upon waking.
  • Aftereffects, though not as severe as MDMA, may linger for a couple of days.

Reference dosage

Reference ranges from third-party harm-reduction databases. Individual response varies enormously — start lower than you think.

Any route
threshold60mg+
light100mg+
common100mg+
strong160mg+
heavy250mg+

Reagent testing

Recommended reagents
Expected reactions
MarquisPurple → black
MeckeBlue → black
FroehdeBlue/green → dark
Simon'sNo reaction (primary amine)

Adulterant detection: Beta-keto MDMA analogue. Reagent profile similar to MDMA; Simon's negative distinguishes it. Often found as MDMA adulterant.

Simon's test: methylone (primary amine) gives no reaction; MDMA (secondary amine) gives blue. Important distinction.

Source

Reference fields and narrative for Methylone extracted from The Drug Users Bible by Dominic Milton Trott (MxZero Publishing, 2022).

drugusersbible.com

Harm reduction notice

This platform provides educational and harm-reduction information adapted from public reference material. It does not endorse, encourage, or facilitate drug use. It is not medical advice. If you or someone near you may be in a medical emergency, contact local emergency services immediately.